Generally, you should make edits to your pets in your software, in Adopt a Pet. Your software's automated import or AutoUpload will push the changes to Adopt a Pet. Edits appear within 12 hours, often much faster.
Exceptions:
1. There is one special field you can edit directly on Adopt a Pet that won't be erased by the next upload: YouTube Video URL
2. Deleting glitch stuck pets: If the software or our system hiccups and pets are not correctly deleted, but have been outcomed or are no longer available in your software, you can delete them from your Adopt a Pet My Pet List.